DPP4 anticorps
Aperçu rapide pour DPP4 anticorps (ABIN7472924)
Antigène
Voir toutes DPP4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- Recognizes human Dipeptidyl peptidase 4, also known as Adenosine deaminase complexing protein 2, CD26, TP103, ADABP or DPP IV. CD26 is a 766 amino acid ~110 kD single pass type II transmembrane glycoprotein expressed by activated T cells, B cells and macrophages. A soluble form of CD26 can be derived by cleavage of the membrane bound form between residues 38-39. CD26 acts as a functional receptor for the pathogenic Middle East respiratory syndrome coronavirus [MERS-CoV], a severe and frequently fatal disease in humans and marmosets sharing identical CD26 sequence at the site of interaction with the MERS-CoV spike protein. Has been used successfully for the immunohistochemical detection of CD26 on formalin fixed, paraffin embedded tissues and the demonstration of elevated CD26 expression in thyroid neoplasia. Has also been used for the immunohistochemical detection of CD26 on cryostat sections using both immunoperoxidase and immunofluorescence staining in liver biopsies from NASH patients.
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Purification
- Protein G purified
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Immunogène
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Human T-cell leukaemia cells (T-CLL).
Type of Immunogen: Cells -
Isotype
- IgG1
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Indications d'application
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Approved: Flo (1:50 - 1:100), IHC, IHC-Fr, IP
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. Method sheets are available on request. -
Commentaires
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, pH 7.4, 0.09 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid freeze-thaw cycles.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- DPP4 (Dipeptidyl-Peptidase 4 (DPP4))
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Autre désignation
- DPP4 / CD26
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Sujet
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Name/Gene ID: DPP4
Subfamily: Serine S9B
Family: Protease
Synonyms: DPP4, ADCP-2, ADABP, Dipeptidyl peptidase IV, Dipeptidyl-peptidase 4, DPPIV, ADCP2, T-cell activation antigen CD26, CD26, CD26 antigen, Dipeptidyl peptidase 4, Dipeptidylpeptidase 4, DPP IV, TP103 -
ID gène
- 1803
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UniProt
- P27487
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Pathways
- Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity
Antigène
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